Cryptococcal meningitis: epidemiology and therapeutic options

Clusters of nosocomial meningitis associated with a single anesthesiologist.

Pitfalls Associated With the Use of Molecular Diagnostic Panels in the Diagnosis of Cryptococcal Meningitis

We report the case of a kidney transplantation patient on chronic immunosuppressive therapy presenting with subacute meningitis. The final diagnosis of cryptococcal meningitis was delayed due to 2 false-negative cryptococcal results on a molecular diagnostic panel. Caution with such platforms in suspected cryptococcal meningitis is needed.

Cryptococcal meningitis in Rio de Janeiro

The objective of this article was to evaluate the epidemiology of cryptococcal meningitis in Rio de Janeiro State, Brazil, from 1994 to 2004. Six hundred and ninety-six cases of cryptococcal meningitis were reported, with a mean incidence of 0.45 per 100,000 inhabitants. Patients were predominantly male; mean age was 35.9 years; AIDS was practically the only underlying disease, reported in 61.2...

The Effect of Therapeutic Lumbar Punctures on Acute Mortality From Cryptococcal Meningitis

INTRODUCTION Cryptococcal meningitis is the most common cause of adult meningitis in sub-Saharan Africa. Raised intracranial pressure (ICP) is common in cryptococcosis. Prior studies suggest elevated ICP is associated with mortality, and guidelines recommend frequent lumbar punctures (LPs) to control ICP. However, the magnitude of the impact of LPs on cryptococcal-related mortality is unknown. ...

Official information systems for cryptococcal meningitis, state of Rio de Janeiro, Southeastern Brazil.

The study aimed to compare the epidemiological profile of crytococcal meningitis in different information systems, thus assessing to what extent the profile available in the Sistema de Informação de Agravos de Notificação (Information System for Notifiable Diseases) reflected cryptococcal meningitis occurrences in the state of Rio de Janeiro, Southeastern Brazil, between 2002 and 2004. That dat...